Pedigree

Menu: [patient] -> [pedigree]

Pedigrees describe family relationships, and marks samples as “affected/unaffected”

This and can be used to filter for inheritance models (eg recessive/dominant) in an analysis.

For the common case of 3 samples, perhaps use a Trio

To create a pedigree

• Create a .ped file for your family, eg using the Phenotipes editor

• Upload the .ped file to VariantGrid

• Match the ped file family and cohort samples to create a Pedigree

• Use an analysis PedigreeNode to apply inheritance models